Artificial cells, blood substitutes,synthetic cell nanomedicine, regenerative medicine, cell encapsulation, gene therapy, enzyme therapy, cell therapy, tissue engineering,dult stem cells, bioencapsulation, nanocapsules, synthetic cellnanotechnology,synthetic cell  nanobiotechnology, microcapsules, drug delivery, liver support

 

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ARTIFICIAL CELLS for general audience

(1) WHAT? WHEN? WHY? HOW? Artificial Cells Click here,

(2) Inventor of artificial cells voted "THE GREATEST MCGILLIAN" in McGill’s 190 years history

     (Click here for result of voting)

(3) 60th Anniversary of Artificial Cells: 

      Youtube addresses and anniversary lecture   https://youtu.be/NtwVAep6RDk 

      www:  addresses  www.artcell.mcgill.ca/addresses.m4v  

                 lecture www.medicine.mcgill.ca/artcell/60AC.mov  

(4) 电视 [人世界]: 加拿大 人科学家明瑞:克服困 研究出人工

        http://people.cctv.com/m/a/index.shtml?id=ARTI6IPLK2vvWJ2kzsQqIbWi1809153 

 

RECENT PLENARY LECTURE (video):

ARTIFICIAL CELLS (SYNTHETIC CELLS):  inventions, translations & routine clinical uses

www.artcell.mcgill.ca/final8.mp4  https://youtu.be/9uNYyf3XVw8 

 

 ARTIFICIAL CELLS AND ORGANS RESEARCH CENTRE 
Artificial Cells and Organs Research Centre organization chart: 

International Network for Artificial Cells Blood Substitute & Biotechnology (ISABI) 

TMS Chang Detailed CV & Publications 

 明瑞院士  

TMS Chang Brief CV

 

SELECTED RECENT SCIENTIFIC REVIEWS AND PAPERS 

(1)   REVIEW ON ARTIFICIAL CELLS: 2019 open access

(2) REVIEW ON HEMOPERFUSION 2017 Opening chapter in 2017 book 

(3) REVIEW ON BLOOD SUBSTITUTES chapter1 in 2021 book

      www.medicine.mcgill.ca/artcell/2021Chapter1.pdf

      www.medicine.mcgill.ca/artcell/2021book.pdf

(4) PAPERS ON NOVEL NANOBIOTHERAPEUTIC WITH ENHANCED RBC FUNCTIONS 

     2017 summary  

     2015 90 mins Hemorrhagic shock   

     2018 Long term safety and immunology   

    2015 Extraction of needed enzymes  :

     2016 Temperature stability 4C to 70C  

(5) 2021 Nanobiotherapeutic for melanoma: J Artificial Cell Nanomedicine Biotech https://doi.org/10.1080/21691401.2021.1918134

      

BOOKS free open access

 

Free online reading

BOOK 2021 Nanobiotherapeutic based Blood Substitutes Edited By TMS Chang, L Bulow, J Jhar, H Sakai, C Yang  www.medicine.mcgill.ca/artcell/2021book.pdf

 

Free download and online reading

(1)   MONOGRAPH 2007 by Chang ARTIFICIALCELLS: biotechnology, nanotechnology, regenerative medicine, blood substitutes bioencapsulation and cell/stem cell

 (2) "BLOOD SUBSTITUTES: principles,methods,products & clinical trials" Chang1997Monograph                                                                                                                             

 (3) "ARTIFICIAL CELLS" Monograph by Chang (1972).(full text of book posted with copyright permission)         

 

READING AND VIDEOS FOR GENERAL AUDIENCE.  

(1 "The Greatest McGillian" in McGill's 190 years history  

Interview: (Click  here for PC) (Click here for Apple)  

Ceremony dinner followed by football kickoff (Click here for PC) (Click here for App)

(2) Chinese Canadian Legend 

     Chapter (Chinese then English 中文其次英文)   

     Video (English) www.medicine.mcgill.ca/artcell/legend.mp4

     Video (Cantonese) www.medicine.mcgill.ca/artcell/fairchild.mp4

(370th Anniversary PRC Book Chapter (中文

(4) Inventing Artificial cells (Chinese(中文) with permission from Sept Days      

(5) Video interview on artificial cells and blood substitutes (needs high speed internet and a few minutes for downloading)

(6) Inventor and 50 years of Artificial Cells (Chinese(中文)) with permission from Ming Poa News          

(7) Father of Artificial Cells (Chinese(中文) 2012 Shantou              

(8) Father of Artificial Cells (Chinese(中文)) 2016 permission of author    

(9) "Father of artificial cells" (Chinese(中文)) Shantou News 

(10 )The Red Blood Cell Man by Andre Picard (Artificial Cells & blood substitutes)          

(11) Blood substitute (French)  

 

CONGRESS OF 60th ANNIVERSARY OF ARTIFICIAL CELLS 

in conjunction with XVI ISBS (Int Sym Blood Substitutes) V ISNS (Nanomedicine)

A. Videos from opening ceremony  

(1)   Addresses followed by 60th anniversary lecture  

     YOUTUBE addresses and opening lecture  

WWW: addresses  Opening lecture

 (2) PLENARY LECTURES:  

Prof Jiang’s group:conduit for reconnecting nerve     

Prof Jahr: clinical use of Polyhemoglobin blood substitute 

Prof Prakash Artificial Cells for microbiome and cardiac stents             

B. ABSTRACT BOOK:

 

EARLIER SCIENTIFIC REVIEWS  
(1) Detailed review on "Artificial Cells" from 2005 Nature Review Drug Discovery    

 (2) "Nanobiotechnology based blood substitutes" from 2006 Trends in Biotechnology        

 (3) "Nanobiotechnological modification of hemoglobin and enzymes” from 2008 Biochimica et Biophysica Acta:          

(4) "Nanobiotechnology for hemoglobin-based blood substitutes" Preprint from 2009 Critical Care Clinics Clinics          

(5)  Artificial Red Blood Cells, Oxygen Carriers, Oxygen Therapeutics to Artificial Cells and Nanomedicine &beyond.  Opening remarks XIII ISBS      

(6) Artificial Cells: the beginning of Nanomedicine 2013 Chapter 1 in book on Selected Topics in Nanomedicine 2013   


PUBLIC ISSUES ON BLOOD SUBSTITUTES 
(1) Krever commission's Report on Blood Suply in Canada implemented by Quebec   

(2)   Is there a priority to include blood substitutes in national blood supply policies? 

(3)   Is there a role for first generation blood substitutes in hemorrhagic shock?   

(4)   Is there a need for blood substitutes in the new millennium safety and efficacy?

by Chang,Greenburg,Chen,Feola & Simoni, Tsuchida, Biro, Yang, Alayash, Bucci, Hsia. 

(5)   Safety of red blood cell substitutes as compared to stored donor red blood cells 

(6)   Blood Substitutes in 2010 

 

TEACHING MATERIAL (For McGill students only) 
www.medicine.mcgill.ca/artcell/518.pdf